Classifying ‘Unmada’ as psychiatric, psychological or psychosomatic disorder only limits the understanding of this vast but seldom understood subject. In Charaka Samhita, the clear etiopathogenesis and subsequent line of treatment indicates both internal pathology as well as external causes including but not limited to diet, mental strength, physical injury and emotional trauma. However, irrespective of the etiopathogenesis, a strong focus on the use of Ghrita based medication to consumption of ghee as it has been observed in relation to internal medication. This perspective study discussed references and possible mode of action of Ghrita, especially Purana Ghrita (old clarified butter) in treatment of mind related pathologies.
Agnivesha, Charaka Samhita with Ayurvedadipika commentary by Chakrapanidatta; Varanasi; Chaukhamba Orientalia; Reprint 2009; Page-738, 467-468, 471-73.
Singh, Jyoti. Critical Review of Unmadgajakesari Rasa A Herbomineral Formulation. International Journal of Applied Ayurved Research. 2022;2(8):1069-1075.
Swatmarama: The Hatha yoga pradeepika with English translation, edited by pancham sinh. Munshiram Manoharlal publishers pvt ltd. 2014, p.51 31.
Mishra B., Shri. Vaidya Rupalalji, BhavprakashNighantu 11th Ed. Chaukhamba Sanskrit Bhavan Varanasi, 2007, Page no. 776.
Susrutha:Susrutha Samhitha with Nibanda sangraha commentary of Delhana edited by Yadavji Trikamji Acharya.2nd ed. Chaukamba Krishnadas academy. 2001, Sutra Sthana 15/2
Madhavi A, H P S, Shetty SK, C H A, Hussain G. A CRITICAL REVIEW ON THE USAGE OF GHRITA IN UNMADA. J Biol Sci Opin 2016;4:148–52. https://doi.org/10.7897/2321-6328.04436.
Rathi, Bharat and Rajput, Dhirajsingh and Wanjari, Anita and Khan, Mujahid. Physico - Chemical Analysis of Purana Ghrita (Old Clarified Butter) with special reference to Fatty Acid Profile. Journal of Indian System of Medicine. 2018;6(1):4-9.
Fulkar SN, Aher PA, Joshi MR. A Study of Ghrita Kalpana with special reference to Charak Samhita. International Ayurvedic Medical Journal. 2014;2(5):780-787. Available from http://www.iamj.in/posts/2014/images/upload/ 780_787.pdf
Kinoshita M. Targeted drug delivery to the brain using Jolesz FA. Magnetic Resonance Imaging-Guided Focused Ultrasound. Topics in Magnetic Resonance Imaging 2006;17:137–8. https://doi.org/10.1097/rmr.0b013e3180332722
Pardridge WM. Drug Transport across the Blood–Brain Barrier. J Cereb Blood Flow Metab 2012;32:1959–72. https://doi.org/10.1038/jcbfm.2012.126.
Upadhyay RK. Drug Delivery Systems, CNS Protection, and the Blood Brain Barrier. BioMed Research International 2014;2014:1–37. https://doi.org/10.1155/2014/869269.
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright (c) 2023 Tanvi Dayanand